Meaning of "Can't Fight Biology" by Drop Dead, Gorgeous

The lyrics of "Can't Fight Biology" delve into the complexities of a tumultuous relationship where the speaker is fully aware of the toxicity and damage caused by their partner, yet finds themselves unable to break free. The repetition of phrases like "it's a mistake" and "you wear me out" highlights a sense of resignation and helplessness in the face of a situation that the speaker knows is not good for them. The imagery of gripping a blade, hiding feelings, being tainted, and feeling overrated paints a picture of intense emotional turmoil and manipulation. The mention of running away and feeling afraid to be oneself indicates a desire to escape from the destructive relationship but a fear of losing what little sense of self they have left. Ultimately, the speaker seems to grapple with the idea of feeling trapped by their own choices and unable to change the presence of their partner in their life, leading to a profound sense of internal conflict and struggle.