Meaning of "Ohio" by The Black Keys

"Ohio" by The Black Keys delves into the themes of isolation, homesickness, and mental struggle. The repetitive choruses of "Whoa, ooh-Whoa" create a sense of longing and yearning for something beyond reach, possibly symbolizing the elusive feeling of home. The mention of being overtaken by the road to the point of blindness and feeling alone even in familiar places speaks to a deeper emotional state of the narrator. The line "Break your back and never wonder why" could suggest a sense of resignation and acceptance of hardship without questioning. Ultimately, the song captures a yearning for connection, a desire for familiarity, and a struggle to find peace amidst the chaos of the mind.